Phenotype Image Detail

Image

Caption

Sequential sitll images of ependymal cilia from wild-type (+/+, A) and Hydin^hy3/Hydin^hy3 (-/-, B) mice. The time is indicated in milliseconds. In B, three moving cilia are tracked with arrowheads. Bars, 5 um. C-F: Ciliary waveform in the wild-type (C and D) and mutants (E and F). Line tracings of the effective stroke (C and E) and the recovery stroke (D and F) are shown. In C and D, the frame numbers are indicated. Ciliary positions are shown every 5 or 10 ms for the wild-type and mutant, respectively. The line tracings are from different videos than those shown in panels A and B; E and F are from a Hydin^{hy3-Tg(Bdnf)459Ove}/Hydin^{hy3-Tg(Bdnf)459Ove} (OVE459) mouse. Arrows indicate the direction of movement of the cilia.

Copyright

This image is from Lechtreck KF, J Cell Biol 2008 Feb 11;180(3):633-43, and is displayed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported License. J:135322

Associated Alleles

Symbol	Name
Hydin^hy3	HYDIN, axonemal central pair apparatus protein; hydrocephalus 3
Hydin^hy3-Tg(Bdnf)459Ove	HYDIN, axonemal central pair apparatus protein; transgene insertion 459, Paul Overbeek

Associated Genotypes

Allelic Composition	Genetic Background
Hydin^hy3-Tg(Bdnf)459Ove/Hydin^hy3-Tg(Bdnf)459Ove	FVB/N-Hydin^hy3-Tg(Bdnf)459Ove
Hydin^hy3/Hydin^hy3	involves: FVB/N