Phenotype Image Detail

Image

Caption

Analysis of ciliary coordination. Images and image analysis from wild-type (A,B,E,F and I) and Hydin^hy3/Hydin^hy3 brain (C,D,G,H, and J). A and C: Average of eight frames of ependymal cilia in top view; moving cilia appear as lines. B and D: The plane of ciliary beating was marked by lines using three images, each representing an average of eight frames and showing cilia in top view. E-H: Images (E and G) showing the lines used to generate scans and the corresponding line scans (kymograms; F and H). F: The diagonal lines marked by arrows result from the coordinated sequential movement of wild-type cilia. H: The line scans for the mutant break up into tracks of individual cilia, revealing their different ciliary beat frequencies (CBFs, arrows and dots). The horizontal parts of the scan marked by dots indicate stalling of the cilium. I and J: Orientation of the basal feet in the ependymal epithelium from wild-type (I) and mutant (J) mice. Bars, 1 um.

Copyright

This image is from Lechtreck KF, J Cell Biol 2008 Feb 11;180(3):633-43, and is displayed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported License. J:135322

Associated Alleles

Symbol	Name
Hydin^hy3	HYDIN, axonemal central pair apparatus protein; hydrocephalus 3

Associated Genotypes

Allelic Composition	Genetic Background
Hydin^hy3/Hydin^hy3	involves: FVB/N