Phenotype Image Detail

Image

Caption

Skeletal preparation of a newborn Fgf9^Eks/Fgf9^Eks (Eks/Eks) (A,D,E,J), Fgf9^Eks/Fgf9⁺ (Eks/+) (B,F,G,K) and wild-type (+/+) (C,H,I,L) mice are shown. Overviews of the entire forelimbs (A,B,C), higher magnification views of elbow joint (D,F,H), histological examinations of the elbow joints (E,G,I), and overviews of the entire hindlimbs (J,K,L) are aligned. Arrows in A,D and E indicate the prospective humeroradial joint. The arrow in J indicates the prospective femurotibial joint. Arrows in B,F and G indicate fusion of the humeroradial joint. Arrows in C,H and I indicate normal humeroradial joints. The arrow in J indicates the presumptive knee joint. The arrow in L indicates the knee joint. The following abbreviations are used: s, scapula; h, humerus; r, radius; u, ulna; fe, femur; t, tibia; fi, fibula.

Copyright

This image is from Murakami H, Mamm Genome 2002 Jul;13(7):341-4 and is displayed with the permission of Springer Science + Business Media, Inc., New York who owns the copyright. J:77537

Associated Alleles

Symbol	Name
Fgf9^Eks	fibroblast growth factor 9; elbow knee synostosis

Associated Genotypes

Allelic Composition	Genetic Background
Fgf9^Eks/Fgf9^Eks	involves: C57BL/6J * DBA/2J
Fgf9^Eks/Fgf9^+	involves: C57BL/6J * DBA/2J