Phenotype Image Detail

Image

Caption

Characteristics of vibrissae of 7 day old and 10-11 week old wild-type, Hr^Hp/Hr⁺ and Hr^Hp/Hr^Hp mice. A: Vibrissae of mutants displayed the same characteristic coat hair: short and curly. Vibrissae were long and straight in wild-type (+/+) mice (b and b'), of both long and straight (c and c'), and short and bent (d and d') in Hr^Hp/Hr⁺ mice, and short and curly in Hr^Hp/Hr^Hp mice (e and e'). F,G: The average number and length of vibrissae were dose-dependently decreased as the number of mutant alleles increased. The wide standard deviation observed in heterozygous mince was attributed to coexistence of long and short types of vibrissae in these mice. H-J: Morphology of a longitudinal section of the vibrissal follicle of 10 week old wild-type or 11 week old heterozygous and homozygous mice. The vibrissae of both wild-type (h) and heterozygous (i) displayed the protruding club hair. Follicles in heterozygous (i') and homozygous (j) showed reduced epidermal epithelial cell growth and an expanded cavernous sinus. Scale bar = 50 um.

Copyright

This image is from Baek IC, Mamm Genome 2009 Jun;20(6):350-8 and is displayed with the permission of Springer Science + Business Media, Inc., New York who owns the copyright. J:150720

Associated Alleles

Symbol	Name
Hr^Hp	lysine demethylase and nuclear receptor corepressor; hairpoor

Associated Genotypes

Allelic Composition	Genetic Background
Hr^Hp/Hr^Hp	BALB/cJ-Hr^Hp
Hr^Hp/Hr^+	BALB/cJ-Hr^Hp