Phenotype Image Detail

Image

Caption

Full-thickness epidermis from the 13 day gestation normal (a) and Sfn^Er/Sfn^Er (b) mice. (a) Cells of basal (B), intermediate (I) and peridermal (P) layers are closely associated and joined by desmosomes (D) in the normal mouse. Some glycogen (Gl) deposits are present in the cytoplasm. (b) In the Sfn^Er/Sfn^Er mouse, cells are widely separated and joined by few desmosomes. A diffuse matrix material is present in the intercellular spaces (arrows). Similar material is associated with the basal lamina. x325.

Copyright

This image is from Holbrook KA, J Cell Biol 1982 Feb;92(2):387-97, and is displayed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported License. J:6708

Associated Alleles

Symbol	Name
Sfn^Er	stratifin; repeated epilation

Associated Genotypes

Allelic Composition	Genetic Background
Sfn^Er/Sfn^Er	involves: 129/Sv * C57BL/6