Phenotype Image Detail

Image

Caption

Cells in basal (a) and superficial (b) regions of Sfn^Er/Sfn^Er head epidermis. (a) Basal (B) and spinous (S) layers are similar to trunk layers. Spinous cells include poorly preserved glycogen deposits (arrows). Granular cells (G) have keratohyalin granules and a marked density of the cytoplasm. x2,100. (b) Three zones of superficial cells (A-B-C). The lower cell (C) retains the nucleus (N). Seven cells in the midzone (B) have keratohyalin granules (KHG), dense bundles of keratin filaments (KF), and abundant ribosomes (arrows). Cells of the most superficial zone (A) have an even greater density and indistinguishable content. Extruded lamellar granules (circled) can be seen between cells. x8,500.

Copyright

This image is from Holbrook KA, J Cell Biol 1982 Feb;92(2):387-97, and is displayed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported License. J:6708

Associated Alleles

Symbol	Name
Sfn^Er	stratifin; repeated epilation

Associated Genotypes

Allelic Composition	Genetic Background
Sfn^Er/Sfn^Er	involves: 129/Sv * C57BL/6