Phenotype Image Detail

Image

Caption

Analysis of collagen in tail tendon. A: Lower power view of cross sectional area of adult tail tendon collagen from Dcn^tm1Ioz/Dcn^tm1Ioz mouse reveals abnormal shape and multiple lateral fusions. Higher power view of mutant tendons shows bizarre, gigantic fibrils (>660 nm in largest diameter) with multiple lateral fusions (B, arrowheads), in contrast with the more uniform collagen fibrils of the wild-type mice (C) with an average of ~200 nm.

Copyright

This image is from Danielson KG, J Cell Biol 1997 Feb 10;136(3):729-43, and is displayed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported License. J:39212

Associated Alleles

Symbol	Name
Dcn^tm1Ioz	decorin; targeted mutation 1, Renato V Iozzo

Associated Genotypes

Allelic Composition	Genetic Background
Dcn^tm1Ioz/Dcn^tm1Ioz	involves: 129S1/Sv * 129X1/SvJ * Black Swiss