Phenotype Image Detail

Image

Caption

Geometry of synapses in Colq^tm1Jrs/Colq^tm1Jrs mice. Longitudinal sections of P20 control (a) and Colq^tm1Jrs/Colq^tm1Jrs muscle were stained with rhodamine-alpha-bungarotoxin. In controls, the postsynaptic membrane contains a set of interconnected AChR-rich gutters. In mutants, some synaptic sites are relatively normal in appearance (b), others appear immature (c), and still others appear fragmented (d). Bar, 10 um.

Copyright

This image is from Feng G, J Cell Biol 1999 Mar 22;144(6):1349-60, and is displayed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported License. J:54006

Associated Alleles

Symbol	Name
Colq^tm1Jrs	collagen like tail subunit of asymmetric acetylcholinesterase; targeted mutation 1, Joshua R Sanes
Colq^tm2Jrs	collagen like tail subunit of asymmetric acetylcholinesterase; targeted mutation 2, Joshua R Sanes

Associated Genotypes

Allelic Composition	Genetic Background
Colq^tm1Jrs/Colq^tm1Jrs	involves: 129S1/Sv * 129X1/SvJ
Colq^tm2Jrs/Colq^tm2Jrs	involves: 129S1/Sv * 129X1/SvJ