Phenotype Image Detail

Image

Caption

Analysis of Fbn2^tm1Rmz/Fbn2^tm1Rmz mouse limbs. A: Forelimbs of wild-type (+/+) and Fbn2^tm1Rmz/Fbn2^tm1Rmz (-/-) newborn mice showing contractures of the wrist and metacarpal joints. B: Skeletal preparation of adult hindlimbs of wild-type and mutant mice with arrow pointing to hard tissue syndactyly in the latter. C: Staining of cartilaginous elements of E13.5 hindlimbs of wild-type and mutant embryos with arrow pointing to digit fusion in the latter.

Copyright

This image is from Arteaga-Solis E, J Cell Biol 2001 Jul 23;154(2):275-81, and is displayed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported License. J:70592

Associated Alleles

Symbol	Name
Fbn2^tm1Rmz	fibrillin 2; targeted mutation 1, Francesco Ramirez

Associated Genotypes

Allelic Composition	Genetic Background
Fbn2^tm1Rmz/Fbn2^tm1Rmz	either: (involves: 129/Sv) or (involves: 129/Sv * C57BL/6J)