Phenotype Image Detail

Image

Caption

Npc1^m1N/Npc1^m1N (Npc1^-/-) sperm were obtained from the cauda epididymides of 60 day old mutant mice. Microscopy analysis revealed a much greater number of abnormal morphology, such as, aberrant head (arrow 1) and headless tail (arrow 2), in the sperm of mutant mice. Arrow 3 illustrates normal sperm morphology. Original magnification, 600x.

Copyright

This image is from Fan J, Mol Reprod Dev 2006 Oct;73(10):1284-91, and is displayed with the permission of Wiley-Blackwell, who owns the Copyright. J:119302

Associated Alleles

Symbol	Name
Npc1^m1N	NPC intracellular cholesterol transporter 1; Niemann Pick type C1 NIH

Associated Genotypes

Allelic Composition	Genetic Background
Npc1^m1N/Npc1^m1N	involves: BALB/c