Phenotype Image Detail

Image

Caption

Electron micrographs of negatively stained plasma lipoprotein fractions of wild-type and Lcat^tm1Hgc/Lcat^tm1Hgc mice. A, VLDL fraction, wild-type (+/+) mice; B, VLDL fraction Lcat^tm1Hgc/Lcat^tm1Hgc (-/-) mice; C, HDL fraction, wild-type mice; and D, HDL fraction mutant mice. The large sized particles in the mutant HDL fraction represent contaminating VLDL/LDL particles. The arrow in B indicates a notched VLDL particle. The bar markers represent 100 nm.

Copyright

This image is from Ng DS, J Biol Chem 1997 Jun 20;272(25):15777-81 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:41208

Associated Alleles

Symbol	Name
Lcat^tm1Hgc	lecithin cholesterol acyltransferase; targeted mutation 1, Edward M Rubin

Associated Genotypes

Allelic Composition	Genetic Background
Lcat^tm1Hgc/Lcat^tm1Hgc	involves: C57BL/6 * DBA