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Caption | Histological analysis of Tg(Dspp-TGFB1)3Kul/? mouse teeth. A: Representative sagittal section of the molar of 15-day-old wild-type mouse stained with hematoxylin and eosin. B: Molar of 15-day-old Tg(Dspp-TGFB1)3Kul/? with a low TGFB1 expression. C: Molar of 15-day-old mutant mice with higher TGFB1 expression. D-F: High magnifications of A-C, respectively. Normal organization of odontoblast layer and orientation of dentinal tubules are seen in wild-type molars. Irregular odontoblast layer and dentinal tubules with cellular inclusions (arrow) are present in mutant molars. de, dentin; od, odontoblasts; p, pulp. | ||||
Copyright | This image is from Thyagarajan T, J Biol Chem 2001 Apr 6;276(14):11016-20 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:118918 | ||||
Associated Alleles |
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Associated Genotypes |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 08/02/2024 MGI 6.24 |
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