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Phenotype Image Detail
Image
Caption Ultrastructural analysis of Tg(Dspp-TGFB1)3Kul/? mouse teeth. Ground sections of incisors from wild-type (A and C) and Tg(Dspp-TGFB1)3Kul/? (B and D) mice. The arrow indicates dentin-enamel junction. Note the highly abnormal and irregular dentin in B. C and D, higher magnifications of dentin in A and B, respectively. The arrow indicates regular dentinal tubules in C and highly disorganized tubules with voids in D. Note the abnormal deposition of dentin extracellular matrix (DECM) with void spaces (arrow) in D. de, dentin; dt, dentinal tubules; en, enamel; md, mantle dentin.
Copyright This image is from Thyagarajan T, J Biol Chem 2001 Apr 6;276(14):11016-20 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:118918
Associated
Alleles
Symbol Name
Tg(Dspp-TGFB1)3Kul transgene insertion 3, Ashok B Kulkarni
Associated
Genotypes
Allelic Composition Genetic Background
Tg(Dspp-TGFB1)3Kul/? FVB/N-Tg(Dspp-TGFB1)3Kul

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory