Phenotype Image Detail

Image

Caption

Gastric hyperplasia in Kcne2^tm1Gwab/Kcne2^tm1Gwab mice. A: Exemplar sections of stomach fundi isolated from wild-type (+/+) and Kcne2^tm1Gwab/Kcne2^tm1Gwab (-/-) mice as indicated and stained with hematoxylin and eosin. Note that the mutant section is shown both at a similar scale to that of wild-type for comparison (upper panels) and at an expanded scale (lower panel) to allow visualization of the entire stomach lining. Asterisk indicates one area of neutrophil infiltration. Scale bars are in the upper right of each panel. B: Exemplar sections of stomach fundi isolated from wild-type and mutant mice as indicated and stained with periodic acid-Schiff (magenta). Scales are similar for each panel (shown in upper right of each panel).

Copyright

This image is from Roepke TK, J Biol Chem 2006 Aug 18;281(33):23740-7 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:116518

Associated Alleles

Symbol	Name
Kcne2^tm1Gwab	potassium voltage-gated channel, Isk-related subfamily, gene 2; targeted mutation 1, Geoffrey W Abbott

Associated Genotypes

Allelic Composition	Genetic Background
Kcne2^tm1Gwab/Kcne2^tm1Gwab	involves: 129S4/SvJae * C57BL/6