Phenotype Image Detail

Image

Caption

Lung histology of E18.5 fetal wild-type, Abca3^tm1Dgen/Abca3⁺, and Abca3^tm1Dgen/Abca3^tm1Dgen littermates. Paraffin sections of lungs from three E18.5 littermates of an Abca3^tm1Dgen/Abca3⁺ cross were stained with hematoxylin and eosin. a, wild-type mouse had normal lung histology. b, Abca3^tm1Dgen/Abca3⁺ mouse had thicker septa compared with wild-type mouse. c, Abca3^tm1Dgen/Abca3^tm1Dgen mouse lung was less well developed than either wild-type or heterozygous mice. Scale bar, 50 um.

Copyright

This image is from Cheong N, J Biol Chem 2007 Aug 17;282(33):23811-7 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:124809

Associated Alleles

Symbol	Name
Abca3^tm1Dgen	ATP-binding cassette, sub-family A member 3; targeted mutation 1, Deltagen

Associated Genotypes

Allelic Composition	Genetic Background
Abca3^tm1Dgen/Abca3^tm1Dgen	involves: 129P2/OlaHsd * C57BL/6J
Abca3^tm1Dgen/Abca3^+	involves: 129P2/OlaHsd * C57BL/6J