Phenotype Image Detail

Image

Caption

Vascular abnormalities seen in some but not all Aip^tm1Bra/Aip^tm1Bra fetuses. Phenotypic comparison of E18.5-19 wild-type (+/+) and Aip^tm1Bra/Aip^tm1Bra (-/-) mice. Comparison of abnormalities in wild-type (left) versus mutant littermates (middle and right). A, decreased number and caliber of vessels within the vascular network of the yolk sac in mutant mice. Vessels indicated by red arrow. B, presence of hemorrhage and petechiae along upper torso. Hemorrhage and petechiae indicated by red arrows.

Copyright

This image is from Lin BC, J Biol Chem 2007 Dec 7;282(49):35924-32 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:141575

Associated Alleles

Symbol	Name
Aip^tm1Bra	aryl-hydrocarbon receptor-interacting protein; targeted mutation 1, Christopher A Bradfield

Associated Genotypes

Allelic Composition	Genetic Background
Aip^tm1Bra/Aip^tm1Bra	involves: 129S4/SvJaeSor * C57BL/6