Phenotype Image Detail

Image

Caption

Histological analyses of testis, epididymides, and testicular sperm. Cross-sections of Rsph1^tm1Htan/Rsph1⁺ (+/-, A and B) or Rsph1^tm1Htan/Rsph1^tm1Htan (-/-, C-F) testis are shown. B and D-F show testicular tubules under high magnification. Arrows and an asterisk indicate irregularly arranged spermatocytes and round spermatids, respectively. Cross-sections of heterozygous (G and I) or homozygous (H and J) epididymides are shown. G and H show caput epididymides and I and J show cauda epididymides. Sperm was not found in homozygous mutant epididymides (H and J). Heterozygous (K and L) and homozygous mutant (M-P) testicular sperm were observed. The heads of the homozygous mutant sperm have abnormal features (O and P). Bar = 50 um.

Copyright

This image is from Tokuhiro K, J Biol Chem 2008 Jul 4;283(27):19039-48 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:138122

Associated Alleles

Symbol	Name
Rsph1^tm1Htan	radial spoke head 1 homolog (Chlamydomonas); targeted mutation 1, Hiromitsu Tanaka

Associated Genotypes

Allelic Composition	Genetic Background
Rsph1^tm1Htan/Rsph1^tm1Htan	involves: 129S1/Sv * C57BL/6J