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Caption | Development of the epidermal permeability barrier. A, littermate E18.5 embryos stained with toluidine blue indicates loss of ABCA12 function (Abca12tm1Lex/Abca12tm1Lex) increases inward permeability to this dye. B, loss of ABCA12 function significantly increases outward transepidermal water loss rates as measured in littermate E18.5 embryos using the gravimetric assay. (Abca12+/+, n=3; Abca12+/-, n=7; Abca12-/-, n=6; +/- S.E.: p= 0.11, Abca12 +/+ versus Abca12 +/-; p=0.00005, Abca12+/+ versus Abca12-/-). | ||||
Copyright | This image is from Zuo Y, J Biol Chem 2008 Dec 26;283(52):36624-35 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:144062 | ||||
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Associated Genotypes |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 10/29/2024 MGI 6.24 |
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