Phenotype Image Detail

Image

Caption

E, transmission electron micrograph of the aortic wall of a wid-type mouse showing a smooth muscle cell (SMC) and the collagen (marked with C) and elastic layers (marked with E). F, degeneration of the aortic wall in a 1 month old Plod1^tm1Soin/Plod1^tm1Soin male mouse. A degenerated smooth muscle cell (X) and a viable smooth muscle cell (SMC) with dilated endoplasmic reticulum (arrow) are shown. Scale bar, 2 um.

Copyright

This image is from Takaluoma K, J Biol Chem 2007 Mar 2;282(9):6588-96 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:120891

Associated Alleles

Symbol	Name
Plod1^tm1Soin	procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1; targeted mutation 1, Raija Soininen

Associated Genotypes

Allelic Composition	Genetic Background
Plod1^tm1Soin/Plod1^tm1Soin	involves: 129S6/SvEvTac * C57BL/6