Phenotype Image Detail

Image

Caption

A: A Dgat1^tm1Far/Dgat1^tm1Far (Dgat1^-/-) mouse photographed at 8,9, and 11 weeks of age. Note the first appearance of alopecia (white box) in the dorsal caudal skin region at 9 weeks of age and complete regrowth of hair in the same region (white box) by 11 weeks of age. B: A mutant mouse photographed at 5 and 7 months of age. Note the different locations of alopecia (boxed areas) at two ages. C: Adhesive tape test of dorsal hair loss in P28, P52, and P63 wild-type and mutant mice (n = 3/genotype/time point; each tape represents hair from a different mouse. D: Quantification of hiar removed by adhesive tape (n = 3/genotype/time point). *, p <0.001 versus wild-type.

Copyright

This image is from Shih MY, J Biol Chem 2009 Feb 13;284(7):4292-9 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:147611

Associated Alleles

Symbol	Name
Dgat1^tm1Far	diacylglycerol O-acyltransferase 1; targeted mutation 1, Bob Farese

Associated Genotypes

Allelic Composition	Genetic Background
Dgat1^tm1Far/Dgat1^tm1Far	involves: 129S4/SvJae * C57BL/6J