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Caption | Analysis of collagen fibrillogenesis in corneas. Transmission electron microscopy illustrates the difference between wild-type corneal stroma (a) and Lmx1btm1Rjo/Lmx1btm1Rjo stroma (b) at 10,000x, Arrows in (a) indicate the orthogonal arrangement of collagen fibrils between keratocytes (k) in the wild-type. The asterisk in (b) indicates electron lucent space in mutant corneal stroma. The boxed areas in (a,b) represent sections examined at 50,000x in (c and d). Cross sections through collagen fibrils reveal that fibril diameter is larger in mutant corneas (d, arrow) than in wild-type corneas (c, arrow). (a,b) White scale bars = 500nm. (c,d) White scale bars = 100nm. | ||||
Copyright | This image is from Pressman CL, Genesis 2000 Jan;26(1):15-25, and is displayed with the permission of Wiley-Blackwell, who owns the Copyright. J:60307 | ||||
Associated Alleles |
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Associated Genotypes |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 08/27/2024 MGI 6.24 |
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