Phenotype Image Detail

Image

Caption

Characterization of the developmental defects of the Pdgfc^tm1.1Hdin/Pdgfc^tm1.1Hdin embryos. (B) A coronal section of E15.5 wild-type embryo shows the fusion of palate shelves. (C) On the contrary, the Pdgfc^tm1.1Hdin/Pdgfc^tm1.1Hdin embryo developed cleft palate as two palate shelves (PS) did not fuse at the midline at E15.5. In addition, these mutant embryos also had the formation of subepithelial blister in the nasal septum (arrow indicated).

Copyright

This image is from Wu X, Genesis 2007 Oct;45(10):653-7, and is displayed with the permission of Wiley-Blackwell, who owns the Copyright. J:128709

Associated Alleles

Symbol	Name
Pdgfc^tm1.1Hdin	platelet-derived growth factor, C polypeptide; targeted mutation 1.1, Hao Ding

Associated Genotypes

Allelic Composition	Genetic Background
Pdgfc^tm1.1Hdin/Pdgfc^tm1.1Hdin	involves: 129 * C57BL/6 * FVB/N * SJL