Phenotype Image Detail

Image

Caption

Uterine morphology at nine months of age. The Errfi1^tm1.1Jwj/Errfi1^tm1.1Jwj ((Mig-6^-/-) uterus is diffusely enlarged compared to the wild-type (WT,A). By light microscopy, the mutant uterus (B) has an increased number of endometrial glands compared to the wild-type (C). At higher magnification, the mutant uterus (D) has hyperplasia of both luminal and glandular epithelia, characterized by stratification of epithelial cells, nuclear enlargement, and the presence of highly branched glands. These microscopic features were absent in the wild-type uterus (E).

Copyright

This image is from Jin N, Genesis 2007 Nov;45(11):716-21, and is displayed with the permission of Wiley-Blackwell, who owns the Copyright. J:129106

Associated Alleles

Symbol	Name
Errfi1^tm1.1Jwj	ERBB receptor feedback inhibitor 1; targeted mutation 1.1, Jae-Wook Jeong

Associated Genotypes

Allelic Composition	Genetic Background
Errfi1^tm1.1Jwj/Errfi1^tm1.1Jwj	involves: 129 * C57BL/6 * FVB/N * SJL