Phenotype Image Detail

Image

Caption

Histological sections of the costal-sternal junctions in wild-type (a, 2.5x; c and e, 10x) and Bmal1^tm1Bra/Bmal1^tm1Bra (b, 2.5x; d and f 10x) mice. Proliferative bone bridging from the costal cartilage to the sternum is evident in the mutant mice. (b,d, black arrowheads). The perichondrium overlying rib in mutant mice (f) shows abnormal increased matrix deposition compared to wild-type mice (f, white arrowhead).

Copyright

This image is from Bunger MK, Genesis 2005 Mar;41(3):122-32, and is displayed with the permission of Wiley-Blackwell, who owns the Copyright. J:97108

Associated Alleles

Symbol	Name
Bmal1^tm1Bra	basic helix-loop-helix ARNT like 1; targeted mutation 1, Christopher A Bradfield

Associated Genotypes

Allelic Composition	Genetic Background
Bmal1^tm1Bra/Bmal1^tm1Bra	B6.129-Bmal1^tm1Bra