Phenotype Image Detail

Image

Caption

Detail of myocardial lesions and staining for cleaved caspase 3. a-d: Detail of typical sections of myocardial wall from Cxadr^tm1Rwf/Cxadr⁺ (+/-) ~10.8 dpc embryos at 600x magnification. e-h: Detail of myocardial wall lesions from Cxadr^tm1Rwf/Cxadr^tm1Rwf (-/-) ~10.8 dpc embryos at 600 x magnification. Panels on the left show hematoxylin and eosin stained sections while panels on the right show staining for cleaved caspase 3 (brown/black). The myocardial cells in the center of the lesions stained positively for the apoptotic marker cleaved caspase 3.

Copyright

This image is from Asher DR, Genesis 2005 Jun;42(2):77-85, and is displayed with the permission of Wiley-Blackwell, who owns the Copyright. J:99585

Associated Alleles

Symbol	Name
Cxadr^tm1Rwf	coxsackie virus and adenovirus receptor; targeted mutation 1, Robert W Finberg

Associated Genotypes

Allelic Composition	Genetic Background
Cxadr^tm1Rwf/Cxadr^tm1Rwf	involves: 129S6/SvEvTac * C57BL/6