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Phenotype Image Detail
Image
Caption Transmission electron micrographs of spinal cord and dorsal root ganglion (DRG) pathology of Pi4k2aGt(AK0094)Wtsi/Pi4k2aGt(AK0094)Wtsi mice. (A and B) Shown is accumulated glycogen in a spinal cord axon. (Scale bars: 1 um). (C and D) Macrophages engulfing degenerate spinal cord axons are shown. (Scale bars: C, 10 um; D, 5 um). (E) A DRG growth cone packed with multivesicular bodies and (F) a degenerate axon from a DRG are shown. (Scale bars: 1 um).
Copyright This image is from Simons JP, Proc Natl Acad Sci U S A 2009 Jul 14;106(28):11535-9. Copyright 2009 National Academy of Sciences, U.S.A. J:150794
Associated
Alleles
Symbol Name
Pi4k2aGt(AK0094)Wtsi phosphatidylinositol 4-kinase type 2 alpha; gene trap AK0094, Wellcome Trust Sanger Institute
Associated
Genotypes
Allelic Composition Genetic Background
Pi4k2aGt(AK0094)Wtsi/Pi4k2aGt(AK0094)Wtsi involves: 129P2/OlaHsd * BALB/c
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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09/17/2024
MGI 6.24 		The Jackson Laboratory