Phenotype Image Detail

Image

Caption

Impaired erythropoeisis in Ppp1r15b^tm1Dron/Ppp1r15b^tm1Dron (Ppp1r15b-/-) mice. (B) Photograph of Wright's stained blood smears from E18.5 wild-type (WT) and mutant mice. Barbed arrows indicate nucleated cells; plain arrows indicate echinocytic (deformed) cells. (C) Photomicrograph of hematoxylin- and eosin- (H&E) stained liver sections of E16.5 WT and mutant mice. (Magnification: Upper, 5x; Lower, 20x).

Copyright

This image is from Harding HP, Proc Natl Acad Sci U S A 2009 Feb 10;106(6):1832-7. Copyright 2009 National Academy of Sciences, U.S.A. J:144954

Associated Alleles

Symbol	Name
Ppp1r15b^tm1Dron	protein phosphatase 1, regulatory subunit 15B; targeted mutation 1, David Ron

Associated Genotypes

Allelic Composition	Genetic Background
Ppp1r15b^tm1Dron/Ppp1r15b^tm1Dron	involves: 129P2/OlaHsd