Phenotype Image Detail

Image

Caption

Embryonic skin obtained from the trunks of wild-type (+/+) mice (uppermost row), heterozygous Cdsn^tm1Mmat/Cdsn⁺ (+/-) mice (second row from top), and homozygous Cdsn^tm1Mmat/Cdsn^tm1Mmat (-/-) mice (third row from top) was grafted onto the backs of nude mice. Gross appearance of the grafted skins 2 weeks (left) and 4 weeks (right) after transplantation. Thin and slightly curly hairs from skin of homozygous mutant mice at 2 and 4 weeks after transplantation are shown from different angles bottom most row. Representative results of one mouse for each group examined (wild-type, n=2; heterozygous, n=4; homozygous, n=3) are shown.

Copyright

This image is from Matsumoto M, Proc Natl Acad Sci U S A 2008 May 6;105(18):6720-4. Copyright 2008 National Academy of Sciences, U.S.A. J:134613

Associated Alleles

Symbol	Name
Cdsn^tm1Mmat	corneodesmosin; targeted mutation 1, Mitsuru Matsumoto

Associated Genotypes

Allelic Composition	Genetic Background
Cdsn^tm1Mmat/Cdsn^tm1Mmat	involves: C57BL/6 * CBA