Gene Expression Image Detail

Reference

Figure

ID

J:153498 Diez-Roux G, et al., PLoS Biol. 2011;9(1):e1000582

6

MGI:4881803

Image

Caption

(A) Each transcript is depicted with a different color to show how the expression of each gene in pallial cells is complementary to others, with some degree of overlap . (B) Picture of a mid-sagittal section of the brain from a section series of a Eurexpress assay processed with Cresyl violet. The inserts show the area where the corresponding regions (arrows) have been localized. It is important to note the homogeneity of cellular patterns in the mantle layer of the thalamus and spinal cord, as opposed to the complex molecular patterns observed in (C) and (D). (C)The merged picture, using a color for each gene (right panel), shows how molecular regionalization allows detection of differences in cell identities in the four areas of thalamic mantle layer. (D) Sagittal section of the spinal cord, showing an overlay picture where the expression patterns of four genes have been combined. The picture summarizes the localization of region-specific molecular codes in spinal cord cells. These molecular codes correspond to different structural levels of the developing spinal cord. The merged color composites are the product of alignment, superposition of sections, and editing using a computer program. Labels: ventricular epithelium (VZ); subventricular zone (SVZ) ; intermedial zone (IZ); mantle layer (ML); marginal zone. (MZ).; retroflexus tract (rf); prethalamus (PTh); dorsal thalamus (DTh); anterior thalamus (ATh); ventral thalamus(VTh); posterior thalamus (PTh) ; commissural nuclei of pretectum (COM); eminentia thalami (EPTh); epithalamus (ET); medial pallium (MP); precommisural nuclei of pretectum (PC); prehalamic tegmentum (PThTg); pretectal tegmentum (PTTg); thalamic tegmentum (TTg); zona incerta (ZI); gelatinous substance (SG, Rexed's layer 2); motoneurons (MN); central nucleus of the dorsal horn (NP, Rexed's layers 3 and 4); spinal reticular nucleus (Rt, Rexed's layers 5 and 6); visceral motoneurons (vMN).

Copyright

This image is from Diez-Roux G, PLoS Biol 2011;9(1):e1000582, and is displayed under the terms of the Creative Commons Attribution 4.0 International License.

Associated
Assays

Label	Assay & Result Details (Gene Symbol)	Spatial Mapping
A 2610306H15Rik	MGI:4824846 (Fgfbp3)
A Nin	MGI:4826711 (Nin)
A Nhlh1	MGI:4826704 (Nhlh1)
A Hist1h1d	MGI:4825376 (H1f3)
A Rorb	MGI:4827790 (Rorb)
C BC055811 left	MGI:4825546 (Igsf21)
C BC055811 right	MGI:4825546 (Igsf21)
C Pde10a left	MGI:4827116 (Pde10a)
C Pd310a right	MGI:4827116 (Pde10a)
C Btbd3 left	MGI:4823514 (Btbd3)
C Btbd3 right	MGI:4823514 (Btbd3)
D	MGI:4823000 (Adcyap1) MGI:4826008 (Lrrtm1) MGI:4826704 (Nhlh1) MGI:4829281 (Zdhhc2)
C composite	MGI:4823514 (Btbd3) MGI:4823594 (Calb1) MGI:4825546 (Igsf21) MGI:4827116 (Pde10a)
A composite	MGI:4824846 (Fgfbp3) MGI:4825376 (H1f3) MGI:4826704 (Nhlh1) MGI:4826711 (Nin) MGI:4827790 (Rorb)