Phenotype Image Detail

Image

Caption

Phenotype of Jag2^tm2.2Grid/Jag2^tm2.2Grid mutant fetuses. (a-c) Cleft palate in Jag2^tm2.2Grid/Jag2^tm2.2Grid mutant mice. Coronal sections of E16.5 embryos show that the mutant has cleft palate and fused tongue. (c) Fusion of the tongue with the unelevated palatal shelves in the mutant mouse (black arrow). (d,e) Limb defects in mutant mice. A forefoot (left) and hindfoot (right) of E16.5 mouse are shown in each panel. Mutant embryos (e) exhibit syndactyly of both fore- and hindlimbs.

Copyright

This image is from Xu J, Genesis 2010 Jun;48(6):390-3, and is displayed with the permission of Wiley-Blackwell, who owns the Copyright. J:163652

Associated Alleles

Symbol	Name
Jag2^tm2.2Grid	jagged 2; targeted mutation 2.2, Tom Gridley

Associated Genotypes

Allelic Composition	Genetic Background
Jag2^tm2.2Grid/Jag2^tm2.2Grid	involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ * C57BL/6J