Phenotype Image Detail

Image

Caption

Irf6^clft1/Irf6^clft1 mutants form a skin premeability barrier. Wild-type (wt, a,b) and Irf6^clft1/Irf6^clft1 (clft1, c,d) embryos at E16.5 were treated with toluidine blue to assess skin differentiation. Wild-type embryos have almost complete exclusion of the dye while mutants are slightly delayed in forming the barrier.

Copyright

This image is from Stottmann RW, Genesis 2010 May;48(5):303-8, and is displayed with the permission of Wiley-Blackwell, who owns the Copyright. J:160190

Associated Alleles

Symbol	Name
Irf6^clft1	interferon regulatory factor 6; cleft palate 1

Associated Genotypes

Allelic Composition	Genetic Background
Irf6^clft1/Irf6^clft1	involves: A/J * FVB