Phenotype Image Detail

Image

Caption

High-power images of the histology of wild-type and Del(11Cxcl16-Zmynd15)1Ifc/Del(11Cxcl16-Zmynd15)1Ifc (Zmynd15^-/-) testes (A-C) Normal testicular histology showing robust spermatogenesis in wild-type mice. (D-F) Severe depletion of spermatids, mainly the late spermatids (elongating and elongated spermatids) in the seminiferous epithelium of Del(11Cxcl16-Zmynd15)1Ifc/Del(11Cxcl16-Zmynd15)1Ifc testes. The severity of spermatid depletion varies from tubules to tubules, but generally stages I-VIII tubules tend to display more severe spermatid depletion compared than stages IX-XII tubules do. Spermatogonia and spermatocytes appear to be normal. Scale bar=20um.

Copyright

This image is from Yan W, J Biol Chem 2010 Oct 8;285(41):31418-26 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:166802

Associated Alleles

Symbol	Name
Del(11Cxcl16-Zmynd15)1Ifc	deletion, Chr 11, Israel F Charo

Associated Genotypes

Allelic Composition	Genetic Background
Del(11Cxcl16-Zmynd15)1Ifc/Del(11Cxcl16-Zmynd15)1Ifc	involves: 129S4/SvJae * C57BL/6