Phenotype Image Detail

Image

Caption

Ultrastructural morphology of the surface and core of Slc26a4^loop/Slc26a4^loop mineralized bodies. A and B, bisected calcite minerals of P0 utricle. A, the interior facet of bisected mineral shows a smooth surface similar to the exterior surface of the mineral. B, high magnification of the interior surface. C-E, surface of different mineralized bodies isolated from Slc26a4^loop/Slc26a4^loop saccule presented with high power SEM images. C, calcium carbonate (calcite) minerals of P0 mice have a smooth and clean surface. D, highly disordered calcite minerals of 7-month-old saccules revealed a surface that is pitted and fissured (arrows). This stone contained domains that resemble the morphology of calcium oxalate in the form of weddellite (circled). E, calcium oxalate (weddellite) mineral of 10-month-old saccules show a smooth and clean surface. Scale bars equal 25 um in panels A, 5 um in panel B, and 10 um in panels C-E. n = 6.

Copyright

This image is from Dror AA, J Biol Chem 2010 Jul 9;285(28):21724-35 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:163655

Associated Alleles

Symbol	Name
Slc26a4^loop	solute carrier family 26, member 4; loop

Associated Genotypes

Allelic Composition	Genetic Background
Slc26a4^loop/Slc26a4^loop	involves: C3HeB/FeJ