Phenotype Image Detail

Image

Caption

Cranial suture histology and collagen expression in wild-type and Lmna^Dhe/Lmna⁺ mice, 6 weeks post partum. Wild-type (+/+, A,C,E G) Lmna^Dhe/Lmna⁺ (Dhe/+, B,D,F,H). Lateral views of teh coronal suture, 5 um paraffin sections. A,B, toluidine blue stain. C,D, diagrams of A and B with the parietal (P) and interparietal (I) bones outlined and highlighted. E-H, in situ hybridization of adjacent sections of collagens type I (E,F) and type III (G,H). Original magnification = 100X. Intensity of the purlish color indicates relative level of the mRNA.

Copyright

This image is from Odgren PR, PLoS One 2010;5(4):e9959, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:160175

Associated Alleles

Symbol	Name
Lmna^Dhe	lamin A; disheveled hair and ears

Associated Genotypes

Allelic Composition	Genetic Background
Lmna^Dhe/Lmna^+	B6(D2)-Lmna^Dhe/TyGrsrJ