Phenotype Image Detail

Image

Caption

Histopathological analysis of amyloid in different organs in the Zdhhc13^skc4/Zdhhc13^skc4 mice. Amyloid deposition in sinusoids and around the portal vein in liver (A); in red pulp and peri-white pulp area in spleen (B). In kidney, amyloid was found in glomerulus (C) and renal tubules (D). Amyloid was also found in adrenal cortex and medulla (E), islet of Langerhans and around the acinar cells of pancreas (F), salivary glands (G) and myocardium (arrows in H). All sections were stained with Congo red; amyloid deposits appeared pink-red color with this staining. Bar= 100 um.

Copyright

This image is from Saleem AN, PLoS Genet 2010;6(6):e1000985, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:161519

Associated Alleles

Symbol	Name
Zdhhc13^skc4	zinc finger, DHHC domain containing 13; skin/coat 4

Associated Genotypes

Allelic Composition	Genetic Background
Zdhhc13^skc4/Zdhhc13^skc4	involves: 129S6/SvEvTac * C3H * C57BL/6