Phenotype Image Detail

Image

Caption

Histological examination of 13.5 day old embryos revealed that, when compared to age matched wild-type (Uch37^+/+), Uchl5^{Gt(OST447189)Lex}/Uchl5^{Gt(OST447189)Lex} (Uch37^-/-) mice showed undeveloped lateral and third ventricles in forebrain area, with associated disorganized development of the cortex and midbrain as well as undeveloped mesencephalic vesicle and fourth ventricles in midbrain, with disorganized development of cerebellum and hindbrain.

Copyright

This image is from Al-Shami A, PLoS One 2010;5(10):e13654, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:166694

Associated Alleles

Symbol	Name
Uchl5^Gt(OST447189)Lex	ubiquitin carboxyl-terminal esterase L5; gene trap OST447189, Lexicon Genetics

Associated Genotypes

Allelic Composition	Genetic Background
Uchl5^Gt(OST447189)Lex/Uchl5^Gt(OST447189)Lex	involves: 129S5/SvEvBrd * C57BL/6J