Phenotype Image Detail

Image

Caption

Adrm1 deficiency affects body weight and composition. Body weights (A) and composition (B) were measured for wild-type (Rpn13^+/+) and Adrm1^{Gt(OST128063)Lex}/Adrm1^{Gt(OST128063)Lex} (Rpn13^-/-) mice at the time points and intervals shown. Minimum 3, maximum 38 mice were studied at each time point. Numbers above bars indicate P values compared to wild-types. (C) Representative images of CAT-scan analysis of 16-week old male mice with the indicated genotype. An additional male and a female mutant mouse were also analyzed along with wild-type littermates and showed similar increases in fat deposits as marked on the image.

Copyright

This image is from Al-Shami A, PLoS One 2010;5(10):e13654, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:166694

Associated Alleles

Symbol	Name
Adrm1^Gt(OST128063)Lex	adhesion regulating molecule 1 26S proteasome ubiquitin receptor; gene trap OST128063, Lexicon Genetics

Associated Genotypes

Allelic Composition	Genetic Background
Adrm1^Gt(OST128063)Lex/Adrm1^Gt(OST128063)Lex	involves: 129S5/SvEvBrd * C57BL/6J