Phenotype Image Detail

Image

Caption

(A) Hematopoietic cell profile of the indicated tissues harvested from wild-type (Rpn13^+/+), Adrm1^{Gt(OST128063)Lex}/Adrm1⁺ (Rpn13^+/-), and Adrm1^{Gt(OST128063)Lex}/Adrm1^{Gt(OST128063)Lex} (Rpn13^-/-) mice. Data were obtained from 4-5 month old mice (n=15-31) and are presented as mean +/-SEM. Numbers above bars indicate P values compared to wild-type mice. Mono, monocytes; Neutro, neutrophils. (B) Representative picture of thymi from wild-type and mutant mice demonstrating difference in size of the organs. (C) Representative flow cytometric plots show normal CD4/CD8 mAb staining patterns of thymocytes from mice of both genotypes. Samples from 10 additional mice of each genotype gave similar results.

Copyright

This image is from Al-Shami A, PLoS One 2010;5(10):e13654, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:166694

Associated Alleles

Symbol	Name
Adrm1^Gt(OST128063)Lex	adhesion regulating molecule 1 26S proteasome ubiquitin receptor; gene trap OST128063, Lexicon Genetics

Associated Genotypes

Allelic Composition	Genetic Background
Adrm1^Gt(OST128063)Lex/Adrm1^Gt(OST128063)Lex	involves: 129S5/SvEvBrd * C57BL/6J