Phenotype Image Detail

Image

Caption

The wild-type (+/+) in (A) shows the neck region of a sperm cell from a wild-type mouse. In the implantation fossa, several typical components of the connection between head and tail can be idnetified: the basal plate (BP), the capitulum (C), and straited columns (Sc). NE, nuclear envelope; PM, plasma membrane. The image in (B) shows the neck region of a seperated head obtained from a Oaz3^tm1Htan/Oaz3^tm1Htan (-/-) mouse. The basal plate (BP) is apparent at the outer nuclear membrane, but the remaining connecting components (i.e., the capitulum and straited columns) are absent. The image in (C) shows the distal end of the seperated tail. Note that the capitulum (C) and straited columns (Sc) are present. Bar = 0.5 um. (D) Schematic presentation of mature sperm in mutant mice.

Copyright

This image is from Tokuhiro K, PLoS Genet 2009 Nov;5(11):e1000712, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:161751

Associated Alleles

Symbol	Name
Oaz3^tm1Htan	ornithine decarboxylase antizyme 3; targeted mutation 1, Hiromitsu Tanaka