Phenotype Image Detail

Image

Caption

White matter damages and astrogliosis in the caudate putamen and fimbria of hippocampus in 20 month-old Tg(Notch3*R169C)88Bbb/0 mice. Shown are representative sections of caudate putamen (A) and fimbria of the hippocampus (B) from 20 month-old mice expressing wild-type Notch3 (TgNotch3^WT) and Tg(Notch3*R169C)88Bbb/0 (TgNotch3^R169C) mice stained with Kluver-Barrera Luxol fast blue (upper panels) or GFAP (lower panels). Scale bar is 65 um.

Copyright

This image is from Joutel A, J Clin Invest 2010 Feb 1;120(2):433-45 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:156682

Associated Alleles

Symbol	Name
Tg(Notch3*R169C)88Bbb	transgene insertion 88, Norbert Hubner

Associated Genotypes

Allelic Composition	Genetic Background
Tg(Notch3*R169C)88Bbb/0	involves: FVB/N