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Caption | Histopathology of lung from wild-type and Sgpl1Gt(OST58278)Lex/Sgpl1Gt(OST58278)Lex mice. (A) Wild-type (S1PL+/+) lung: Alveolar spaces are generally clear and septa are thin in wild-type mice (B) Sgpl1Gt(OST58278)Lex/Sgpl1Gt(OST58278)Lex (S1PL-/-) lung: Alveoli contain variably sized irregularly shaped polygonal flakes and clumps of smooth homogenous (hyaline) material accompanied by increased numbers of alveolar macrophages. Alveolar septa are mildly thickened due to cellular hypertrophy and collagen deposition. H&E stain. | ||||||
Copyright | This image is from Vogel P, PLoS ONE 2009;4(1):e4112, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:145159 | ||||||
Associated Alleles |
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Associated Genotypes |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 08/02/2024 MGI 6.24 |
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