Gene Expression Image Detail

Reference

Figure

ID

J:142567 Capellini TD, et al., Genesis. 2008 Nov;46(11):683-96

5

MGI:5295063

Image

Caption

Expression is present in the developing notochord (black arrowheads). Interestingly, at E11.5, it is absent in anterior domains (k and black inset l, empty black arrowheads) and minimally present in the notochord at more caudal domains of the embryo (m and red inset n, gray arrowheads). At E11.5, expression appears markedly reduced across all axial levels compared to earlier gestational days. Expression is also present in numerous other domains including: at E9.5, forelimb and hindlimb buds (albeit at very low levels; a, short red arrows), branchial arch 1 (a, long red arrow), and paraxial mesoderm (b, green arrows); at E10.5, at very low levels in both limb types (d, short red arrows), in branchial arch 1 (d, long red arrow), and along the paraxial mesoderm (d, g and h, green arrows); and at E11.5, at higher levels, in both limb types (i, short black arrows), branchial arch and frontal nasal tissues (j, long black arrows), and in a reduced manner in the paraxial mesoderm (j, short red arrows). Dashed red lines in d and j indicate the level of the sections shown in e and m, respectively, whereas the dashed black line in j depicts the level of section k. Small red arrowheads depict areas of probe trapping and background, as revealed by comparisons with sense controls (c, i, o).

Copyright

This image is from Capellini TD, Genesis 2008 Nov;46(11):683-96, and is displayed with the permission of Wiley-Blackwell, who owns the Copyright.

Associated
Assays

Label	Assay & Result Details (Gene Symbol)	Spatial Mapping
a	MGI:5295413 (P3h3)
b	MGI:5295413 (P3h3)
d	MGI:5295413 (P3h3)
e	MGI:5295413 (P3h3)
f	MGI:5295413 (P3h3)
g	MGI:5295413 (P3h3)
j	MGI:5295413 (P3h3)
k	MGI:5295413 (P3h3)
l	MGI:5295413 (P3h3)
m	MGI:5295413 (P3h3)
n	MGI:5295413 (P3h3)
h	MGI:5295413 (P3h3)