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Caption | (A) Pinx1tm1.1Kplu/Pinx1+ heterozygous knockout leads to anaphase bridges and chromosome instability at late passage. MEFs derived from wild-type (+/+) and heterozygous (+/-) littermates were continuously cultured using the 3T3 protocol and fixed at early (from 3 to 5) or late (~30) passage, followed by staining with DAPI to score for the frequency of anaphase bridges and/or lagging chromosomes. | ||||
Copyright | This image is from Zhou XZ, J Clin Invest 2011 Apr 1;121(4):1266-82 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:171997 | ||||
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Associated Genotypes |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 12/10/2024 MGI 6.24 |
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