Phenotype Image Detail

Image

Caption

Immunohistochemical detection of Tcfap2c expression on intestinal sections of Col1a1^{tm1(tetO-Tcfap2c)Hsc}/Col1a1⁺ Gt(ROSA)26Sor^{tm1(rtTA*M2)Jae}/Gt(ROSA)26Sor⁺ (Tcfap2c) (A) and control (ctrl) mice (B). (C) Ratio of crypt length/villus length the area indicated. Length of villus was measured as the distance from the intestinal muscularis mucosa to the villus-apex; length of the crypts was measured as distance from muscularis mucosae to the bottom of the villus. ***p<=0.0001, **p<=0.001, Scale bar = 100 um.

Copyright

This image is from Holl D, PLoS One 2011;6(7):e22034, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:174049

Associated Alleles

Symbol	Name
Col1a1^tm1(tetO-Tcfap2c)Hsc	collagen, type I, alpha 1; targeted mutation 1, Hubert Schorle
Gt(ROSA)26Sor^tm1(rtTA*M2)Jae	gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Rudolf Jaenisch

Associated Genotypes

Allelic Composition	Genetic Background
Col1a1^tm1(tetO-Tcfap2c)Hsc/Col1a1^+ Gt(ROSA)26Sor^tm1(rtTA*M2)Jae/Gt(ROSA)26Sor^+	involves: 129S4/SvJae * C57BL/6