Phenotype Image Detail

Image

Caption

Reduced sympathetic nerve activity in Ffar3^tm1Gzt/Ffar3^tm1Gzt (Gpr441-/-) mice. (D and E) Anti-tyrosine hydroxylase (TH) antibody immunostaining (brown) in superior cervical ganglion (SCG) at P1. Total volume was measured by quantifying the TH-positive area (n = 6). (F) (Upper) Whole-mount immunostaining of the heart with anti-TH antibodies (brown). (Lower) High magnification view. (Scale bar: 1 mm.) (G) Quantitative analysis of TH+ nerve areas (n = 5). (H) TH protein expression (n = 6). Beta-actin (loading control). Mice were analyzed at 12 weeks of age (F-H). *P < 0.05; **P < 0.005.

Copyright

This image is from Kimura I, Proc Natl Acad Sci U S A 2011 May 10;108(19):8030-5. Copyright 2011 National Academy of Sciences, U.S.A. J:172798

Associated Alleles

Symbol	Name
Ffar3^tm1Gzt	free fatty acid receptor 3; targeted mutation 1, Gozoh Tsujimoto

Associated Genotypes

Allelic Composition	Genetic Background
Ffar3^tm1Gzt/Ffar3^tm1Gzt	involves: C57BL/6