Phenotype Image Detail

Image

Caption

Whole body computerized tomographic (CT) images reveal subcutaneous ossifications in Gnas^tm1Gwa/Gnas⁺ mice. CT scans of 12 month (A-D) and 3 month (E, F) male and female Gnas^tm1Gwa/Gnas⁺ mice with heterozygous targeted disruption of exon 1 in the Gnas gene. Arrows indicate a subset of the subcutaneous ossifications. (A) male, maternally inherited allele (-m/+), (B) female, -m/+, (C) male, paternally inherited allele (+/-p), (D) female, +/-p. (E) male, -m/+. (F) female, -m/+.

Copyright

This image is from Huso DL, PLoS One 2011;6(6):e21755, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:174525

Associated Alleles

Symbol	Name
Gnas^tm1Gwa	GNAS complex locus; targeted mutation 1, Gary Wand

Associated Genotypes

Allelic Composition	Genetic Background
Gnas^tm1Gwa/Gnas^+	involves: 129S/SvEv * 129S4/SvJae