Phenotype Image Detail

Image

Caption

Unvascularized retinal areas after tamoxifen-inducible Cre-loxP genetic recombination in the oxygen-induced retinopathy (OIR) model. Whole-mount PECAM-1 IHC in P18 OIR retinas of Plxnd1^tm1.1Tmj/Plxnd1^tm1Ddg Tg(CAG-cre/Esr1*)1Egwa/0 (Plxnd1^flox/-) mice after daily i.p. injections of 40HT or vehicle from P12. The unvascularized retinal areas represented in red were measured for the morphometric analyses. Scale bar: 1 mm.

This image is from Fukushima Y, J Clin Invest 2011 May 2;121(5):1974-85 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:173943

Associated
Alleles

Symbol	Name
Plxnd1^tm1.1Tmj	plexin D1; targeted mutation 1.1, Thomas M Jessell
Plxnd1^tm1Ddg	plexin D1; targeted mutation 1, David D Ginty
Tg(CAG-cre/Esr1*)1Egwa	transgene insertion 1, Gyohei Egawa

Associated
Genotypes

Allelic Composition	Genetic Background
Plxnd1^tm1Ddg/Plxnd1^tm1.1Tmj Tg(CAG-cre/Esr1*)1Egwa/0	involves: 129S/SvEv * C57BL/6 * DBA/2

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