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Caption | Absence of renal cilia in Kif3atm1Gsn/Kif3atm2Gsn Tg(Cdh16-cre)91Igr/0 mutant mice. (A-C) Immunostaining of acetylated tubulin (red) and AQP2 (green) in kidneys from control mice (A) and Kif3atm1Gsn/Kif3atm2Gsn Tg(Cdh16-cre)91Igr/0 mutants (B and C) at P21. Arrowheads, primary cilia; cd, collecting duct; hl, loop of Henle; pt, proximal tubule; cy, cyst. Insets show higher-magnification images. (Bar = 10 um.) (D-F) Scanning electron micrographs of kidneys from control mice (D) and mutants (E and F) at P21. Arrowheads, primary cilia; pc, principal cell; ic, intercalated cell; tu, tubule. [Bars = 10 (A-C) and 5 um (D-F).] | ||||||||
Copyright | This image is from Lin F, Proc Natl Acad Sci U S A 2003 Apr 29;100(9):5286-91. Copyright 2003 National Academy of Sciences, U.S.A. J:83293 | ||||||||
Associated Alleles |
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Associated Genotypes |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 08/02/2024 MGI 6.24 |
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