Phenotype Image Detail

Image

Caption

(C) Whole-mount platelet/endothelial cell adhesion molecule (PECAM-1) immunohistochemistry (IHC) in P18 oxygen-induced retinopathy (OIR) retinas after tamoxifen-inducible Cre-loxP-mediated genetic recombination. Gt(ROSA)26Sor^{tm1(CAG-Rhoj,-EGFP)Auem}/Gt(ROSA)26Sor^{tm1(CAG-Rhoj,-EGFP)Auem} Tg(CAG-cre/Esr1*)1Egwa/0 (R26-Rhoj) mice were i.p. injected with 4OHT daily from P12. For the control mice, vehicle (1:9 ethanol/sunflower oil) was injected into mutants. Scale bars: 100 um (C). Error bars represent SEM; ***P < 0.001, **P < 0.01.

Copyright

This image is from Fukushima Y, J Clin Invest 2011 May 2;121(5):1974-85 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:173943

Associated Alleles

Symbol	Name
Gt(ROSA)26Sor^tm1(CAG-Rhoj,-EGFP)Auem	gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Akiyoshi Uemura
Tg(CAG-cre/Esr1*)1Egwa	transgene insertion 1, Gyohei Egawa

Associated Genotypes

Allelic Composition	Genetic Background
Gt(ROSA)26Sor^tm1(CAG-Rhoj,-EGFP)Auem/Gt(ROSA)26Sor^tm1(CAG-Rhoj,-EGFP)Auem Tg(CAG-cre/Esr1*)1Egwa/0	involves: C57BL/6 * CBA * DBA/2