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Phenotype Image Detail
Image
Caption Mirc5tm1Jae/Mirc5tm1Jae primordial germ cells (PGCs) are delayed in entering the hindgut. Images of primordial germ cells (PGCs) in E8.5 wild-type embryos expressing a GFP transgene driven by Pou5f1 (Oct4) promoter (WT) for visualization of PGCs (A) and Mirc5tm1Jae/Mirc5tm1Jae embryos expressing this transgene (mir-290-295-/-) (B and C). Numbers in parentheses refer to the number of somite pairs present in each embryo. Arrows point to groups of PGCs. (Scale bars, 100 uM).
Copyright This image is from Medeiros LA, Proc Natl Acad Sci U S A 2011 Aug 23;108(34):14163-8. Copyright 2011 National Academy of Sciences, U.S.A. J:175228
Associated
Alleles
Symbol Name
Mirc5tm1Jae microRNA cluster 5, including Mir290a through Mir295; targeted mutation 1, Rudolf Jaenisch
Associated
Genotypes
Allelic Composition Genetic Background
Mirc5tm1Jae/Mirc5tm1Jae involves: 129S4/SvJae * C57BL/6
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory